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Introduction: The burden of chronic kidney disease has been increasing more in developing
countries like Ethiopia. It is the leading cause of End Stage renal disease (ESRD) which has a
significant impact in mortality and health care cost associated with diabetes. There are only few
studies done in that was done in Diabetic Mellitus and hypertension in Ethiopia, and there is no
research done in government facilities until recently. Since there is availability of diagnostic
mechanisms it might show different result compared to government hospitals.
Objectives: To determine the magnitude and factors associated with chronic kidney disease on
diabetic and hypertensive patients in Addis Ababa Yekatit 12 Hospital Medical College, 2024
Methods: An institution based Cross sectional study design was conducted using simple random
sampling technique. A total of 304 patients were enrolled in the study at Yekatit12 Hospital
Medical College. Data was collected by using by interviewer. A facilitator was trained to undertake
the data collection process. After the collected data is cleaned, checked for completeness and
accuracy that to be analyzed in SPSS version 26.To find substantially linked determinants of CKD
in people with diabetes and hypertension, bivariate and multivariate logistic regression analysis
will be employed.
Results: Out of 304 participants; 98% respondents and the proportion of developing kidney
disease were 13% .Factors associated with chronic kidney disease are have family history of
kidney disease [(AOR=0.08, 95%CI: 0.002-0.9), P<0.05]; smoking [(AOR=0.29, 95%CI: 0.002
0.5), P<0.05], hemoglobin A1C is greater than >7% [(AOR=0.11, 95%CI: 0.01-0.7),
P<0.05],high-density lipoprotein greater than or equal to 40 mg/dl (AOR = 0.28, 95% CI: 0.003
0.3)] and normal bilirubin direct level (AOR = 0.013, 95% CI: 0.001-0.12, P<0.01) were found to
be significantly associated with chronic kidney disease.
Conclusion and recommendation: In this finding, the proportion of chronic kidney disease was
13%, and factors like A1C, high-density lipoprotein, hemoglobin A1C, and B (d) are strongly
linked. Regular monitoring, lifestyle modifications, and managing risk factors like diabetes or high
cholesterol can reduce the risk of developing the disease. Early detection and management can
prevent or slow its progression.
............. Thesis available at ACIPH Library |
en_US |